科研细胞

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药靶细胞

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产物编号

CBP10423

货号:

CBP10423

品牌:

Cobioer

规格:

1ug

物种:

构造:

数目

库存:

产物描写

参数

产物数据库

CBP10423
Format	Genomic DNA
Description	BRAF is a member of the RAF family that is activated by members of the Ras family upon growth factor-induced stimulation. Active Ras can induce heterodimerization of cRaf and BRAF and this may explain the observed cooperativity of cRaf and BRaf in cells responding to growth factor signals. Activating mutations in the BRAF gene are present in a large percentage of human malignant melanomas and in a proportion of colon cancers. The vast majority of these mutations result in a valine to glutamic acid change at residue 600 within the activation segment of B-RAF .

Technical Data
DNA Change	c.1799_1800TG>AT
AA Change	p.V600D
Mutation type	Substitution - Missense
Zygosity	Homozygous
Allelic Frequency	100%
Transcript	ENST00000288602
Buffer	Tris-EDTA

Product Information
Intended Use	Research Use Only
Unit Size	1ug
Concentration	Download for COA
Purofication	Download for COA
DNA electrophoresis	Download for COA
Sanger sequencing
Storage	-20℃
Expiry	36 months from the date of manufacture