科研细胞

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药靶细胞

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产物编号

CBP10425

货号:

CBP10425

品牌:

Cobioer

规格:

1ug

物种:

构造:

数目

库存:

产物描写

参数

产物数据库

CBP10425
Format	Genomic DNA
Description	BRAF, serine/threonine-protein kinase B-raf, is a member of the Raf family of serine/threonine protein kinases, which signals through the MAP kinase pathway to regulate cell proliferation and cell growth (PMID: 24737949, PMID: 29540830). BRAF mutations have been identified in a variety of cancers, including, colorectal (PMID: 30122982), lung (PMID: 29729495), thyroid (PMID: 12970315), and melanoma (PMID: 24737949), and a number of mutations have also been demonstrated to confer drug resistance (PMID: 27478040).

Technical Data
DNA Change	c.1798G>A
AA Change	p.V600M
Mutation type	Substitution - Missense
Zygosity	Homozygous
Allelic Frequency	100%
Transcript	ENST00000288602
Buffer	Tris-EDTA

Product Information
Intended Use	Research Use Only
Unit Size	1ug
Concentration	Download for COA
Purofication	Download for COA
DNA electrophoresis	Download for COA
Sanger sequencing
Storage	-20℃
Expiry	36 months from the date of manufacture